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U of R looking for volunteers in vaccine trial

Rochester, N.Y.-  The University of Rochester Medical Center is looking for volunteers to take part in an international study that will evaluate the safety and effectiveness of a vaccine aimed at blocking C. diff infections.

The hardy bacteria and its tough-to-kill spores is a leading healthcare-associated infection impacting hospitals, long-term care facilities and communities nationwide.

The greatest burden typically falls upon older patients undergoing a course of antibiotics, which disrupt the guts normal bacterial flora, allowing C. diff to multiply furiously and leak toxins that ravage a patients intestinal lining.

The infection can delay a patients discharge by days and push his or her complete recovery back by months.

Vaccination could prove to be an important way to control these infections and improve health care for everyone, said Dr. John Treanor, URMCs Chief of Infectious Disease.

Treanor, who practices at Strong Memorial Hospital, will enroll vaccine study subjects seen there and at affiliate Highland Hospital. Dr. Ann Falsey, who practices at Rochester General Hospital, will enroll subjects being treated there.

URMC joins more than 200 sites across 17 countries in the Cdiffense clinical trial.

Interested volunteers should be 50 or older and planning an upcoming surgical procedure that requires hospitalization lasting more than 72 hours. Patients in this age group who have had at least two hospital stayseach lasting more than 72 hoursand have received systemic antibiotics in the past year are also eligible.

For more information, call 585-273-3990 (for patients seen at Strong Memorial and Highland) or 585-922-5944 for patients treated at Rochester General Hospital, or visit

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Washington Times